DIAGNOSTIC VALUE OF GENEXPERT MTB/RIF ASSAY FOR TUBERCULOSIS DIAGNOSIS COMPARED TO TRADITIONAL METHODS

GeneXpert MTB/Rif assay for rapid diagnosis of tuberculosis and detection rifampicin resistance can reduce the time to initiation treatment. Aim. To evaluate sensitivity specificity compared with traditional methods detecting Mycobacterium (smear microscopy, culture on liquid solid media). Material methods. The results sputum tests (MBT) by bacteriological molecular genetic in 1355 patients diagnosed during 2016-2020 years were analyzed. Results. informative value was no different method (for infiltrative TB - 78.4% vs. 80.9%, p=0.138; disseminated TB, 75.0% versus 79.0%, p=0.384) higher smear microscopy 49.8%, р<0.001; 61.9%, p=009). At high accuracy (85.0%), media 89.1% – 67.9%. allows early when clinical radiological signs are not clear. However, due low should be further confirmed classical microbiological diagnostics. Conclusions. this study confirm diagnostic using phthisiology practice, especially newly patients.